{"id":42,"date":"2015-10-21T11:14:47","date_gmt":"2015-10-21T10:14:47","guid":{"rendered":"http:\/\/blog.u-bourgogne.fr\/list-maps\/?page_id=42"},"modified":"2016-06-02T13:50:46","modified_gmt":"2016-06-02T12:50:46","slug":"university-of-southern-denmark","status":"publish","type":"page","link":"https:\/\/blog.ube.fr\/list-maps\/consortium\/beneficiaries\/university-of-southern-denmark\/","title":{"rendered":"University of Southern Denmark"},"content":{"rendered":"<p class=\"titre2\" style=\"text-align: center;font-family: streetvertising;color: #483d8b;font-size: 18px\"><a href=\"http:\/\/www.sdu.dk\/en\/\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-668\" src=\"http:\/\/blog.ube.fr\/list-maps\/wp-content\/uploads\/sites\/34\/2015\/10\/sduphoto.jpg\" alt=\"sduphoto\" width=\"422\" height=\"281\" srcset=\"https:\/\/blog.ube.fr\/list-maps\/wp-content\/uploads\/sites\/34\/2015\/10\/sduphoto.jpg 580w, https:\/\/blog.ube.fr\/list-maps\/wp-content\/uploads\/sites\/34\/2015\/10\/sduphoto-300x200.jpg 300w\" sizes=\"auto, (max-width: 422px) 100vw, 422px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p class=\"titre2\" style=\"text-align: center;color: #483d8b;font-family: streetvertising;font-size: 18px\"><strong style=\"color: #483d8b\">DEPARTMENT OF BIOCHEMISTRY AND MOLECULAR BIOLOGY<\/strong><\/p>\n<p class=\"titre2\" style=\"font-family: calibri;padding-right: 60px;padding-left: 60px;text-align: justify;color: #000000\">Research at the Department of Biochemistry and Molecular Biology (BMB) is essentially about the study of the fundamental processes that control all cell life and development. Studies of how genes are structured and organized, how gene activity is regulated and how gene information via RNA is translated into protein. Proteins typically operate by interacting with other proteins or by transforming the molecules. The study of these processes is an essential element of all research at BMB. Protein function is often regulated by the proteins being modified in various ways, and identification of these modifications is also a key area for the Institute&#8217;s research.<br \/>\nThe Institute&#8217;s research is very internationally oriented and takes place in close cooperation with many international research institutions and enterprises.<\/p>\n<p class=\"titre2\" style=\"text-align: center;color: #483d8b;font-family: streetvertising;font-size: 16px\"><strong style=\"color: #483d8b\">Microbiology and pathogenic bacteria<\/strong><\/p>\n<p class=\"titre2\" style=\"font-family: calibri;padding-right: 60px;padding-left: 60px;text-align: justify;color: #000000\">The Kallipolitis group carries out research on gene regulatory systems in gram-positive bacterial pathogens, including <em style=\"color: #000000\">Listeria monocytogenes<\/em> and Staphylococcus aureus. We focus on understanding how RNA- and protein-based gene regulatory systems control the adaptation of bacterial pathogens to changing and stressful environmental conditions. We are particularly interested in uncovering the biological function and mechanism of action of small, regulatory RNAs. In addition, the nematode Caenorhabditis elegans is being exploited as a model host for the study of host-pathogen relationships. In other on-going research projects, we investigate new strategies for prevention and treatment of bacterial infections.<\/p>\n<p class=\"titre2\" style=\"font-family: calibri;padding-right: 60px;padding-left: 60px;color: #000000\"><strong style=\"color: #000000\">Website :<\/strong> <a style=\"text-decoration: none;font-family: calibri;color: #483d8b\" href=\"http:\/\/www.sdu.dk\/en\/Om_SDU\/Institutter_centre\/Bmb_biokemi_og_molekylaer_biologi\/Forskning\/Forskningsenheder\/BirgitteKallipolitis\">Microbiology and Pathogenic bacteria<\/a><\/p>\n<p class=\"titre2\" style=\"font-family: calibri;padding-right: 60px;padding-left: 60px;color: #000000\"><strong style=\"color: #000000\">Website:<\/strong> <a style=\"text-decoration: none;font-family: calibri;color: #483d8b\" href=\"http:\/\/www.sdu.dk\/en\/\">http:\/\/www.sdu.dk\/en\/<\/a><\/p>\n<p class=\"titre2\" style=\"text-align: center;color: #483d8b;font-family: streetvertising;font-size: 18px\"><strong style=\"color: #483d8b\">ROLE IN THE PROJECT<\/strong><\/p>\n<p class=\"titre2\" style=\"font-family: calibri;padding-right: 60px;padding-left: 60px;text-align: justify;color: #483d8b\"><a style=\"text-decoration: none;color: #483d8b\" href=\"http:\/\/blog.ube.fr\/list-maps\/early-stage-researchers\/patricia-dos-santos\/\">Sub-project 7: Role of non-coding sRNAs in the transmission of <em style=\"color: #483d8b\">L. monocytogenes<\/em> between environments<\/a><\/p>\n<p style=\"color: #483d8b;font-family: streetvertising;text-align: center;font-size: 18px\"><strong style=\"color: #483d8b\">STAFF INVOLVED<\/strong><\/p>\n<p style=\"color: #483d8b;font-family: arial;text-align: left;font-size: 14px;padding-left: 60px\"><strong style=\"color: #483d8b\">Birgitte H.KALLIPOLITIS<br \/>\n<\/strong><\/p>\n<p style=\"text-align: left;padding-left: 60px\"><a href=\"http:\/\/blog.ube.fr\/list-maps\/wp-content\/uploads\/sites\/34\/2015\/10\/BHK.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-667\" src=\"http:\/\/blog.ube.fr\/list-maps\/wp-content\/uploads\/sites\/34\/2015\/10\/BHK.jpg\" alt=\"BHK\" width=\"137\" height=\"183\" srcset=\"https:\/\/blog.ube.fr\/list-maps\/wp-content\/uploads\/sites\/34\/2015\/10\/BHK.jpg 303w, https:\/\/blog.ube.fr\/list-maps\/wp-content\/uploads\/sites\/34\/2015\/10\/BHK-300x401.jpg 300w\" sizes=\"auto, (max-width: 137px) 100vw, 137px\" \/><\/a><\/p>\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px;padding-left: 60px\"><strong style=\"color: #000000\">Education<\/strong><\/p>\n<ul style=\"padding-left: 60px\">\n<li style=\"color: #ffffff\">\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px\">1999-2001 Postdoctoral fellow, Professor Hanne Ingmer\u00b4s research group, Department of Veterinary Microbiology, Royal Veterinary &amp; Agricultural University, Denmark.<\/p>\n<\/li>\n<li style=\"color: #ffffff\">\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px\">1997-1999 Postdoctoral fellow, Professor Poul Valentin-Hansen\u00b4s research group, Department of Molecular Biology, Odense University<\/p>\n<\/li>\n<li style=\"color: #ffffff\">\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px\">1997 Ph.D. in Molecular Biology, Odense University. Title of thesis: \u201cProtein-protein communication in Escherichia coli: Structural and functional features of the CytR\/cAMP-CRP\/DNA repression complex\u201d. Supervisor: Professor Poul Valentin-Hansen.<\/p>\n<\/li>\n<\/ul>\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px;padding-left: 60px\"><strong style=\"color: #000000\">Professional and teaching experience<\/strong><\/p>\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px;padding-left: 60px\">Birgitte H. Kallipolitis holds extensive teaching experience in microbiology and molecular biology courses. Since 2002, principle supervisor for 30 B.Sc. project students and 20 M.Sc. project students. Principle supervisor for 8 Ph.D.-students (2 ongoing).<\/p>\n<ul style=\"padding-left: 60px\">\n<li style=\"color: #ffffff\">\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px;text-align: justify\"><span style=\"padding-right: 60px;color: #000000\">2005-present:<\/span><br \/>\nAssociate professor, Department of Biochemistry and Molecular Biology, University of Southern Denmark.<\/p>\n<\/li>\n<li style=\"color: #ffffff\">\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px\"><span style=\"color: #000000\">2002:<\/span><br \/>\nVisiting scientist, Professor Colin Hill\u00b4s research group, Department of Microbiology, University College Cork, Ireland.<\/p>\n<\/li>\n<li style=\"color: #ffffff\">\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px\"><span style=\"color: #000000\">2001-2004:<\/span><br \/>\nAssistant research professor, Department of Biochemistry and Molecular Biology, University of Southern Denmark.<\/p>\n<\/li>\n<\/ul>\n<p style=\"font-family: calibri;color: #000000;padding-right: 60px;padding-left: 60px\"><strong style=\"color: #000000\">Research Interests<\/strong><\/p>\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px;padding-left: 60px\">The Kallipolitis group focuses on understanding the adaptation of bacterial pathogens to changing and stressful environmental conditions. We study how pathogenic bacteria sense and respond to adverse conditions encountered in the external environment and during infection of a host organism. Furthermore, we are involved in developing new strategies for combating infections caused by<br \/>\nantibiotic resistant bacteria. We are particularly interested in uncovering the biological function and mechanism of action of regulatory sRNAs. The first seven sRNAs in the foodborne human pathogen <em style=\"color: #000000\">Listeria monocytogenes<\/em> were discovered by the Kallipolitis group.<\/p>\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-left: 60px;padding-right: 60px\"><strong style=\"color: #000000\">Publications:<\/strong><\/p>\n<ul style=\"padding-left: 60px\">\n<li style=\"color: #ffffff\">\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px\">Christiansen, J. K., Larsen, M. H., Ingmer, H., S\u00f8gaard-Andersen, L., and Kallipolitis, B. H. (2004). The RNA-binding protein Hfq of <em style=\"color: #000000\">Listeria monocytogenes<\/em>: Role in stress tolerance and virulence. J. Bacteriol. 186: 3355-62.<\/p>\n<\/li>\n<li style=\"color: #ffffff\">\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px\">Christiansen, J. K., Nielsen, J. S., Ebersbach, T., Valentin-Hansen, P., S\u00f8gaard-Andersen, L., and Kallipolitis, B. H. (2006). Identification of small Hfq-binding RNAs in <em style=\"color: #000000\">Listeria monocytogenes<\/em>. RNA, 12: 1383-1396.<\/p>\n<\/li>\n<li style=\"color: #ffffff\">\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px\">Nielsen, J. S., Lei, L. K., Ebersbach, T., Olsen, A. S., Klitgaard, J. K., Valentin-Hansen, P., and Kallipolitis, B. H. (2010). Defining a role for Hfq in Gram-positive bacteria: evidence for Hfq-dependent antisense regulation in <em style=\"color: #000000\">Listeria monocytogenes<\/em>. Nucleic Acids Res. 38: 907-919.<\/p>\n<\/li>\n<li style=\"color: #ffffff\">\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px\">Sievers, S., Sternkopf, E. M. S., Jacobsen, K., Lund, A., Mollerup, M. S., Nielsen, P. K., and Kallipolitis, B. H. (2014). A multicopy sRNA of <em style=\"color: #000000\">Listeria monocytogenes<\/em> regulates expression of the virulence adhesin LapB. Nucleic Acids Res. 42:9383-9398.<\/p>\n<\/li>\n<li style=\"color: #ffffff\">\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;padding-right: 60px\">Sievers S., Lund A., Menendez-Gil P., Nielsen A., Storm Mollerup M., Lambert Nielsen S., Buch Larsson P., Borch-Jensen J., Johansson J., Kallipolitis B. H. (2015). The multicopy sRNA LhrC controls expression of the oligopeptide-binding protein OppA in <em style=\"color: #000000\">Listeria monocytogenes<\/em>. RNA Biol. 12:985-97.<\/p>\n<\/li>\n<\/ul>\n<p class=\"titre2\" style=\"font-family: calibri;padding-right: 60px;padding-left: 60px;color: #000000\"><strong style=\"color: #000000\">Full list of publications:<\/strong> <a style=\"text-decoration: none;font-family: calibri;color: #483d8b\" href=\"http:\/\/findresearcher.sdu.dk:8080\/portal\/en\/persons\/birgitte-h-kallipolitis%28642f37f4-0a2d-459b-8092-0f1b21bebb6d%29\/publications.html?filter=research\">list of publications<\/a><\/p>\n<p class=\"titre2\" style=\"font-family: calibri;padding-right: 60px;padding-left: 60px;color: #000000\"><strong style=\"color: #000000\">Contact: <\/strong><a style=\"text-decoration: none;font-family: calibri;color: #483d8b\" href=\"mailto:bhk@bmb.sdu.dk\">bhk@bmb.sdu.dk<\/a><\/p>\n<p style=\"font-family: calibri;text-align: center;font-size: 18px\"><a style=\"text-decoration: none;font-family: calibri;color: #483d8b\" href=\"http:\/\/blog.ube.fr\/list-maps\/consortium\/beneficiaries\/\"><b style=\"color: #483d8b\">See the others partners beneficiaries<\/b><\/a><\/p>\n<p style=\"font-family: calibri;text-align: center;font-size: 18px\"><a style=\"text-decoration: none;font-family: calibri;color: #483d8b\" href=\"http:\/\/blog.ube.fr\/list-maps\/consortium\/partners-organizations\/\"><b style=\"color: #483d8b\">See the associated partners<br \/>\n<\/b><\/a><\/p>\n<p>&nbsp;<\/p>\n<p class=\"titre2\" style=\"font-family: calibri;color: #000000;font-size: 12px;text-align: center\"><a href=\"http:\/\/blog.ube.fr\/list-maps\/wp-content\/uploads\/sites\/34\/2015\/10\/eulogo.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-557 \" src=\"http:\/\/blog.ube.fr\/list-maps\/wp-content\/uploads\/sites\/34\/2015\/10\/eulogo.jpg\" alt=\"eulogo\" width=\"79\" height=\"46\" srcset=\"https:\/\/blog.ube.fr\/list-maps\/wp-content\/uploads\/sites\/34\/2015\/10\/eulogo.jpg 600w, https:\/\/blog.ube.fr\/list-maps\/wp-content\/uploads\/sites\/34\/2015\/10\/eulogo-300x175.jpg 300w\" sizes=\"auto, (max-width: 79px) 100vw, 79px\" \/><\/a>This project has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under the Marie Sklodowska Curie grant agreement n\u00b0 641984<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; DEPARTMENT OF BIOCHEMISTRY AND MOLECULAR BIOLOGY Research at the Department of Biochemistry and Molecular Biology (BMB) is essentially about the study of the fundamental processes that control all cell life and development. Studies of how genes are structured and organized, how gene activity is regulated and how gene information via RNA is translated into&hellip;<\/p>\n<p class=\"more-link-p\"><a class=\"btn btn-primary\" href=\"https:\/\/blog.ube.fr\/list-maps\/consortium\/beneficiaries\/university-of-southern-denmark\/\">Voir plus &rarr;<\/a><\/p>\n","protected":false},"author":99,"featured_media":0,"parent":13,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-42","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/blog.ube.fr\/list-maps\/wp-json\/wp\/v2\/pages\/42","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.ube.fr\/list-maps\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/blog.ube.fr\/list-maps\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/blog.ube.fr\/list-maps\/wp-json\/wp\/v2\/users\/99"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.ube.fr\/list-maps\/wp-json\/wp\/v2\/comments?post=42"}],"version-history":[{"count":16,"href":"https:\/\/blog.ube.fr\/list-maps\/wp-json\/wp\/v2\/pages\/42\/revisions"}],"predecessor-version":[{"id":1375,"href":"https:\/\/blog.ube.fr\/list-maps\/wp-json\/wp\/v2\/pages\/42\/revisions\/1375"}],"up":[{"embeddable":true,"href":"https:\/\/blog.ube.fr\/list-maps\/wp-json\/wp\/v2\/pages\/13"}],"wp:attachment":[{"href":"https:\/\/blog.ube.fr\/list-maps\/wp-json\/wp\/v2\/media?parent=42"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}